Compounded tirzepatide
Direct Meds vs MEDVi
Quick answer
Direct Meds costs $399 a real month and MEDVi costs $434 — a difference of $35 a month, or $417 a year. Both figures are computed from what each seller actually charges and how often, not from the price on its landing page.
Checked in . Both sellers are re-checked on the same schedule; a price either side changes after that date will not be reflected here until the next check.
Direct Meds or MEDVi?
Direct Meds is the cheaper way to start, at $399 a month against $434 for MEDVi; Direct Meds does not publish what its top dose costs, so ask before you commit past the first month. Judged by the headline prices you would pick MEDVi, advertised at $279 against Direct Meds's $399, and that is the wrong way round once each bill is restated as a calendar month. MEDVi names 48 states; Direct Meds does not say where it ships. Direct Meds received an FDA warning letter in September 2025; MEDVi has none on record.
What each one bills
| Direct Meds | MEDVi | |
|---|---|---|
| True monthly cost | $399 | $434 |
| Advertised as | $399 | $279 |
| Charged | every calendar month | every 4 weeks |
| Each charge | $399 | $399 |
| Price basis | a starting-dose price that climbs | the same at every dose |
| Mandatory recurring fee | none found | none found |
| States it names | not published | 48 states |
| FDA warning letter | yes | none on record |
We earn a commission if you start care through one of the links above, at no extra cost to you. Which of these two is cheaper is computed from what each one bills and nothing else.
Where they actually differ
- They bill on different clocks. Direct Meds charges every calendar month and MEDVi charges every 4 weeks. That alone changes what a “month” costs, which is the whole reason this index recomputes every price.
- One price holds and the other climbs. Direct Meds’s price is a starting-dose price that climbs; MEDVi’s is the same at every dose. See what titration does to an advertised figure.
- What they advertise is not what they bill. MEDVi advertises $279 and bills $434.
How we know
Both figures were read on the seller’s own site and recomputed over a 30.4375-day calendar month from the charge and the billing period it covers. Neither is a seller’s own “/mo”. The full working for each — the charge, the period, the arithmetic and the date it was read — is on its own page: Direct Meds and MEDVi. The method is set out in how we verify.
To compare any two sellers in the index rather than these two, use the comparison tool.