Compounded tirzepatide

Joi + Blokes review

By ·Editor·Reviewed

Joi + Blokes sells compounded tirzepatide only by the quarter: $747 for a three-month supply, charged every 90 days. That averages about $253 a month and includes clinician consultations and unlimited sessions with a health coach. It suits someone who wants coaching and optional lab work alongside the medication, and who is ready to commit three months at a time.

A real month costs$253advertised $249 +$3.63 gap
EvidenceVerified
Billing cycle3-mo
Price across dosesSame at every dose
Where it shipsNot stated
FDA warning letterOne on filestill listed here
Visit Joi + Blokes →

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On this page

Who it suits

Good fit if

  • You want a health coach as your main contact, not just a prescriber.
  • You're interested in lab testing and hormone care from the same clinic.
  • You're comfortable paying for three months of tirzepatide in one charge.

Look elsewhere if

  • You want to try one month before committing, since no monthly plan is sold.
  • You'd need your money back if a clinician turns you down, because the refund page calls all sales final.
  • An FDA warning letter issued in 2026 would put you off.

What you get

The plan covers compounded tirzepatide for weekly injection, insulin-sized needles, dosing support, clinician consultations and health coaching. Coaches range from nurses and dietitians to personal trainers. They can explain results and pass questions to your provider, but they can't prescribe.

Joi + Blokes is a Denver company that also treats menopause, testosterone and longevity goals, with Joi for women and Blokes for men. It doesn't practice medicine itself. Independent clinician groups make the prescribing decisions, and U.S.-licensed pharmacies fill the orders. Diagnostic labs are optional, sold separately, and give your coach and clinician more to work with.

How it works

  1. Add the quarterly tirzepatide subscription to your cart and check out. The charge covers a three-month supply.
  2. Complete the health history form. A partner clinician reviews it, either asynchronously or in a scheduled consult.
  3. If the clinician approves you, the medication ships to your door from a U.S.-licensed pharmacy.
  4. Your health coach stays your point of contact, and you can message the care team as often as you need.
  5. The subscription renews for another three months unless you cancel, and the cart shows the next billing date.

Pros and cons

Pros

  • Unlimited Health Coach visits come with the Joi + Blokes tirzepatide plan.
  • Joi + Blokes takes HSA and FSA payments through Flex at checkout.
  • No membership fee sits on top of the $747 quarterly charge.

Cons

  • The only tirzepatide plan sold is quarterly, so the first charge is $747.
  • The product page mentions a cheaper first month, but the Joi + Blokes cart charges the full quarter.
  • The FDA sent Joi + Blokes a warning letter in June 2026 about false and misleading claims.

Check before you pay

If you're not approved
The coaching FAQ says you'll be refunded right away if a prescription isn't appropriate. The refund page says subscription fees already paid can't be refunded. Get the answer in writing before you pay.
The first charge
Look at the cart total before paying. It should read $747 every three months, with the next bill about 90 days out.
Canceling
Joi + Blokes says you can adjust or cancel the plan at any time. Cancel before the next quarterly renewal to avoid another $747 charge.
FDA warning letter
FDA sent Joi + Blokes a warning letter in June 2026. Read what it covers.

Price

Joi + Blokes costs $253 a month for compounded tirzepatide. It advertises $249. The card is charged $747 every 90 days.

How we got $253

The arithmeticOne month = 30.4375 days

  1. Joi + Blokes advertises

    Read on Joi + Blokes's own site

    $249.00

  2. The card is charged $747.00, not $249.00

    The advertised figure is not the amount that leaves the account.

    + $498.00

  3. And it is charged every 90 days, not every month

    4.06 charges a year, not twelve.

    − $494.37

A real month$252.63

A real month costs $3.63 more than the figure advertised.

Where it sits, and what costs less

$86median $269$434+

163 cheaper · 45%197 dearer · 54%

The most expensive 10 sellers charge between $434 and $649 a month.

  1. Collective$86
  2. Teleios Health$99
  3. Valhalla Vitalitystarting dose$99
  4. RxPepsDirectstarting dose$100
  5. WeightRxstarting dose$125
  6. Joi + Blokes$253

Another 158 sellers are cheaper than Joi + Blokes. The whole cheapest list →

Joi + Blokes against other sellers

Side by side on what each one bills over a calendar month.

All comparisons →

What else this seller sells

The same seller appears in our data for one other medication.

Each figure is a real month for that medication, and none of it is part of the compounded tirzepatide price above. How the two molecules compare at every seller that sells both: compounded tirzepatide vs compounded semaglutide.

FDA has written to this seller

In , FDA sent warning letter 728283 to Joi and Blokes dba Joi + Blokes (Denver, CO). The letter’s subject:

False & Misleading Claims/Misbranded (Telehealth)

Read the letter on fda.gov · The letter names joiandblokes.com — the same site this page links to.

This seller stays in the index, at its real price. A warning letter is something you should see and weigh for yourself — an index that quietly dropped the worst records would be least useful exactly when it matters most. How we screen for these →

Joi + Blokes questions

Is Joi + Blokes legit?
Joi + Blokes is a Denver telehealth company with a named medical director, Dr. Melissa Loseke, DO. Independent licensed clinicians decide on prescriptions. Its tirzepatide is compounded, so the FDA hasn't approved it. The FDA sent the company a warning letter in June 2026 about false and misleading claims.
How much is Joi + Blokes tirzepatide per month?
It's sold only as a quarterly subscription at $747 for three months, which comes to about $253 a month. Joi + Blokes's compounded semaglutide works out to $182 a month on the same quarterly terms.
Does Joi + Blokes take insurance for tirzepatide?
Not for the compounded version, which is cash-pay. Joi + Blokes helps with prior authorizations for FDA-approved weight-loss drugs but doesn't bill insurance directly. HSA and FSA cards work through Flex.
Can you cancel Joi + Blokes?
Yes. The GLP-1 subscription can be canceled at any time, and there's no membership fee. Canceling doesn't refund a quarter you've already paid for.