Compounded tirzepatide
Jyra Health vs NewSelf
Quick answer
Jyra Health costs $229 a real month and NewSelf costs $245 — a difference of $16 a month, or $192 a year. Both figures are computed from what each seller actually charges and how often, not from the price on its landing page.
Checked in . Both sellers are re-checked on the same schedule; a price either side changes after that date will not be reflected here until the next check.
Jyra Health or NewSelf?
Jyra Health is the cheaper way to start, at $229 a month against $245 for NewSelf, and since both charge one price whatever the dose, that gap of $16 holds all the way up. Only Jyra Health reaches Louisiana and Mississippi, while only NewSelf reaches PR, going by where each says it ships. NewSelf received an FDA warning letter in February 2026; Jyra Health has none on record.
What each one bills
| Jyra Health | NewSelf | |
|---|---|---|
| True monthly cost | $229 | $245 |
| Advertised as | $133 | $144 |
| Charged | every calendar month | every calendar month |
| Each charge | $229 | $245 |
| Price basis | the same at every dose | the same at every dose |
| Mandatory recurring fee | none found | none found |
| States it names | 50 states | 49 states |
| FDA warning letter | none on record | yes |
Where they actually differ
- What they advertise is not what they bill. Jyra Health advertises $133 and bills $229; NewSelf advertises $144 and bills $245.
How we know
Both figures were read on the seller’s own site and recomputed over a 30.4375-day calendar month from the charge and the billing period it covers. Neither is a seller’s own “/mo”. The full working for each — the charge, the period, the arithmetic and the date it was read — is on its own page: Jyra Health and NewSelf. The method is set out in how we verify.
To compare any two sellers in the index rather than these two, use the comparison tool.