Compounded tirzepatide
Signos review
At Signos, compounded tirzepatide comes packaged with a continuous glucose monitor, and you can't buy one without the other. Standard-dose tirzepatide charges $329 every 28 days across a 12-week commitment, close to $358 per calendar month. That makes the bundle a better deal for people who will actually wear the sensor.
Who it suits
Good fit if
- You'd wear a glucose sensor and use the readings to adjust meals and activity.
- You can commit to at least 12 weeks of tirzepatide before deciding whether to continue.
- You live in any state or DC and want a program that ships nationwide.
Look elsewhere if
- You want tirzepatide without paying for a sensor and an app.
- You need the freedom to quit after four weeks with no fee.
- The $199 starting figure on the plans page is your budget, because standard-dose tirzepatide costs more.
What you get
Signos+ is one price for the medication, the Stelo sensors made by Dexcom, the Signos app and clinical support. Each sensor is worn for 15 days. The app pairs the glucose readings with meal photos, barcode scans and workout logs, and a dietitian is available by chat.
Tirzepatide comes in two versions at checkout, standard and microdose. The $199 per month on the plans page belongs to microdose on a 24-week term. Standard tirzepatide on the 12-week term is $329 a charge, and choosing 24 weeks brings each charge down.
Clinicians from OpenLoop Health, a separate company, decide whether to prescribe. Signos' terms list the four pharmacies OpenLoop contracts with: RedRock Pharmacy, Health Warehouse, Precision Medicine and Triad Rx. The service covers all 50 states plus Washington, D.C.
How it works
- Take the GLP-1 quiz from the Signos plans page. It asks about your health history, current medications and goals.
- Choose tirzepatide, standard or microdose, then a 12-week or 24-week term. The first charge is taken at checkout.
- An OpenLoop clinician reviews your file. If you're disqualified for a medical reason, the payment is refunded in full.
- Once approved, the vial and the sensors arrive in separate packages. Pair the sensor with the Signos app on a phone set to the U.S. app store.
- Two more charges follow every 28 days. At the end of the 12 weeks the plan renews for another term unless you cancel.
Pros and cons
Pros
- Dexcom's Stelo sensor and the Signos app are included, with no separate device fee.
- OpenLoop Health refunds the full payment if its clinician disqualifies you for a medical reason.
- Signos covers all 50 states and Washington, D.C., through four named pharmacies.
Cons
- Signos bills every 28 days, so a year on the 12-week plan means 13 tirzepatide payments.
- Standard tirzepatide at $329 per charge sits well above the $199 headline.
- Leaving before a 12-week Signos term ends may cost an early cancellation fee.
Check before you pay
- Standard or microdose
- The quiz offers both forms of tirzepatide at different prices. Confirm which one your clinician prescribes before you commit to a term.
- Renewal timing
- Cancel in the portal or app under Manage Subscription. The medication terms ask for 72 hours' notice before a billing date, or one more charge goes through.
- What can't be refunded
- Unless a clinician disqualifies you, a canceled subscription earns no refund. Sensors that have shipped can't be returned either.
Price
Signos costs $358 a month for compounded tirzepatide. It advertises $199. The card is charged $329 every 4 weeks.
How we got $358
The arithmeticOne month = 30.4375 days
Signos advertises
Read on Signos's own site
$199.00
The card is charged $329.00, not $199.00
The advertised figure is not the amount that leaves the account.
+ $130.00
And it is charged every 4 weeks, not every month
13.04 charges a year, not twelve.
+ $28.64
A real month$357.64
A real month costs $158.64 more than the figure advertised.
Where it sits, and what costs less
$86median $269$434+
295 cheaper · 81%66 dearer · 18%
The most expensive 10 sellers charge between $434 and $649 a month.
- Collective$86
- Teleios Health$99
- Valhalla Vitalitystarting dose$99
- RxPepsDirectstarting dose$100
- WeightRxstarting dose$125
- Signos$358
Another 290 sellers are cheaper than Signos. The whole cheapest list →
Where it says it operates
Signos is currently available in the United States and ships to all 50 states.
Read on its own site in August 2026. That is the seller’s own promise for the whole country, so confirm your state when you sign up.
State pages this seller appears on: AL AK AZ AR CA CO CT DE DC FL GA HI ID IL IN IA KS KY LA ME MD MA MI MN MS MO MT NE NV NH NJ NM NY NC ND OH OK OR PA RI SC SD TN TX UT VT VA WA WV WI WY
What else this seller sells
The same seller appears in our data for one other medication.
- semaglutide — $271 a month
Each figure is a real month for that medication, and none of it is part of the compounded tirzepatide price above. How the two molecules compare at every seller that sells both: compounded tirzepatide vs compounded semaglutide.
Signos questions
- Is Signos legit?
- Yes. Signos is a metabolic health app company that works with Dexcom's Stelo sensor, and the prescribing is done by licensed clinicians at OpenLoop Health. Signos says its compounded tirzepatide is made in FDA-registered facilities but is not FDA-approved. It is not Zepbound or Mounjaro.
- How much is Signos tirzepatide per month?
- Standard-dose tirzepatide on the 12-week plan is $329 every 28 days, or about $358 a calendar month. The sensors, app and clinician support are inside that charge. The $199 figure advertised on the plans page is the microdose price on the 24-week plan.
- Can you cancel Signos tirzepatide anytime?
- You can switch off renewal at any time, and it takes effect at the end of the current cycle. Canceling in the middle of a 12-week term may bring a fee, and Signos doesn't prorate refunds.
- Does Signos ship tirzepatide to every state?
- Signos' terms say the medication service is offered in all 50 states plus Washington, D.C. It can't ship to APO or FPO military addresses.